Clinical features and presentation of oral potentially malignant disorders

Oral Cancer and Oral Potentially Malignant Disorders

Oral potentially malignant disorders: Is malignant transformation predictable and preventable?

Leukoplakia is the most common potentially malignant disorder of the oral mucosa. The prevalence is approximately 1% while the annual malignant transformation ranges from 2% to 3%. At present, there are no reliable clinicopathological or molecular predicting factors of malignant transformation that can be used in an individual patient and such event can not truly be prevented. Furthermore, foll...

quantitative immunoexpression of egfr in oral potentially malignant disorders: oral leukoplakia and oral submucous fibrosis

background and aims. many oral squamous cell carcinomas develop from potentially malignant disorders (pmds) which include a variety of lesions and conditions characterized by an increased risk for malignant transformation. this study evaluated the quantitative expression of egfr in normal oral mucosa, oral leukoplakia and oral submucous fibrosis to predict the malignant risk in compliance with ...

qat chewing and risk of potentially malignant and malignant oral disorders: a systematic review

background: qat (also known as khat , kat and miraa ) is a green-leaved plant ( catha edulis ). it is a shrub indigenous to yemen and certain parts of eastern africa. chewing the leaves, which have sympathomimetic and euphoric effects, has been documented in many countries and increased with worldwide migration. the effect of long-term chewing qat on the oral cavity is unknown. objective: a sys...

Oral potentially malignant disorders in a large dental population

OBJECTIVES Oral cancer (OC) may be preceded by clinically evident oral potentially malignant disorders (OPMDs). Oral carcinogenesis is a multistep process that begins as epithelial hyperplasia and progresses to oral epithelial dysplasia and finally to fully malignant phenotypes. The aim of our study was to estimate the prevalence of OPMDs in a large population of dental patients. METHODS Pati...